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Anne-Claude Gavin

Anne-Claude Gavin

CMU, University of Geneva

  • Full Professor

About Anne-Claude Gavin

The Gavin lab has a strong research interest in the study of lipid metabolism and the regulation of cellular membranes homeostasis, and their roles in some human pathologies, e.g. infections and Alzheimer, with a special focus on the machinery involved in the creation and maintenance of lipid gradients in eukaryotic cells, and the study of mechanisms by which lipid signatures are sensed and “read” by effector proteins. The lab research programs integrate biochemical, mass spectrometry, proteomics, microfluidics and bioinformatics  to map cellular protein-lipid interactions at molecular levels, both spatially and temporally.

Anne-Claude Gavin was born and raised in Geneva. She studied biology/biochemistry at the University of Geneva, achieving a PhD in biology under the supervision of Dr Sabine Schorderet-Slatkine. She then moved to the European Molecular Biology Laboratory in Heidelberg to study the biochemical mechanisms that regulate the progression of the cell cycle with Dr. Angel Nebreda. In 2000, she joined the biotech company Cellzome Inc as a funding scientist and Director of the Molecular and Cell Biology division, applying systems biology approaches to characterize cellular networks involved in human pathologies. From 2005 to 2019, she ran her own group in the Structural and Computational Biology Unit at the European Molecular Biology Laboratory, where she pioneered novel (bio)chemical methods to map cellular protein-lipid interaction networks. From April 2019 onwards, she leads her group at the CMU in Geneva, as a Louis-Jeantet professor. Prof. Gavin is the recipient of the First Lipidomics Excellence Award 2019 awarded by Lipotype, a spin-off company from the laboratories of Prof. Dr. Kai Simons and Dr. Andrej Shevchenko of the Max-Planck-Institute of Molecular Cell Biology and Genetics in Dresden, Germany.



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